synergyfinder - Calculate and Visualize Synergy Scores for Drug Combinations
Efficient implementations for analyzing pre-clinical
multiple drug combination datasets. It provides efficient
implementations for 1.the popular synergy scoring models,
including HSA, Loewe, Bliss, and ZIP to quantify the degree of
drug combination synergy; 2. higher order drug combination data
analysis and synergy landscape visualization for unlimited
number of drugs in a combination; 3. statistical analysis of
drug combination synergy and sensitivity with confidence
intervals and p-values; 4. synergy barometer for harmonizing
multiple synergy scoring methods to provide a consensus metric
of synergy; 5. evaluation of synergy and sensitivity
simultaneously to provide an unbiased interpretation of the
clinical potential of the drug combinations. Based on this
package, we also provide a web application
(http://www.synergyfinder.org) for users who prefer graphical
user interface.